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Patients with left ventricular dysfunction should avoid nutritional supplements including coenzyme Q10, carnitine, taurine, antioxidants (vitamin C, vitamin E, beta-carotene), and hormonal therapies (growth hormone or thyroid hormone), as these have unproven benefits and potential risks.
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The American College of Cardiology/American Heart Association (ACC/AHA) guidelines explicitly recommend against the routine use of nutritional supplements in patients with left ventricular dysfunction. The guidelines classify this recommendation as Class III (Level of Evidence: C), indicating potential harm or no benefit
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The ACC/AHA guidelines specifically state that “vitamin C, vitamin E, and beta-carotene supplementation are not recommended with the intent of reducing cardiovascular risk or improving clinical outcomes in patients with stable ischemic heart disease”
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Coenzyme Q10: Despite some studies suggesting potential benefits
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, the ACC/AHA guidelines do not recommend its routine use due to insufficient high-quality evidence.
L-carnitine and Taurine: These supplements lack sufficient evidence for routine use in heart failure management
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