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HPTA Shutdown

John Begum
(@john-begum)
New Member

It is good to understand fertility function prior to steroid use before labeling steroid use as the cause of infertility post use. Plus, many users are not honest with their use, especially in studies and also in regards to consultation with medical professionals. So it is hard to come to any conclusion based on what we read.

There are two references, one which is what everyone has read regarding the man who was supposedly shutdown for from 20 years of steroid abuse. Given Triptorelin cured him. There was another one, I think maybe a french study or something along those lines where a doctor also administered Triptorelin for the same reason, instant cure.

I personally used Triptorelin, instant recovery. LH actually shot over 11 which is above medical reference range. this was after 400mg/wk TrenEnanthate cycle.

I think the issue regarding idiots saying Triptorelin does not work is because they do not allow the ester they are taking to completely leave their system (by using steroidcalc.com’s graph to determine this) as any amount of suppressive androgens in plasma will hamper Triptorelin’s effect.

Also, brain estradiol is a very strong mitigator of HPTA function. So taking a once off 150mg Nolvadex dose with your triptorelin will ensure there is no rebound from Triptorelin.

I have personally trialled this on my self on many occasions and of those who I coach. It works like magic.

It is similar to the small minute minority who experience HPPD from LSD use. the minority is so small that it isnt even a risk factor. This could be also one of them.

Remember, like any other system, HPTA works via feedback loops, just like receptor systems of neurotransmitters within the brain. There is down regulation, but nothing is ever permanent. There is only so much a system can be down regulated. Just like how much a receptor can be activated when a ligand has been bound to. I think it works like 95% -> and higher doses and prolonged activation will only make a fraction of the 95-99.999% activation (for example).


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Topic starter Posted : 10/08/2025 5:11 pm
Kim Ward
(@kim-ward)
New Member

how long should you wait between cycles: the Time On = Time Off rule


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Posted : 10/08/2025 8:11 pm
Marcus Wolf
(@marcus-wolf)
New Member

the importance of magnesium and zinc for natural T recovery


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Posted : 11/08/2025 1:11 pm
Rage Warrior
(@ragewarrior)
New Member

the importance of magnesium and zinc for natural T recovery


ReplyQuote
Posted : 11/08/2025 5:11 pm
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