TUDCA vs NAC vs Milk Thistle

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Are you considering trying TUDCA, NAC or Milk Thistle supplements & confused what may be your best option? With each supplement having its own unique set of advantages, understanding the differences between them is essential. In this blog post we will provide a detailed overview comparing the similarities of TUDCA, NAC & Milk Thistle as well as what sets these three supplements apart.

Tauroursodeoxycholic acid or more simply referred to as TUDCA, is a natural bile acid that is produced in the human body. The liver releases bile salts into the intestines via the bile duct from there the bile salts are then metabolized into ursodeoxycholic acid (UDCA) by microbes in the large intestine. To create TUDCA, the UDCA is conjugated with a taurine molecule. Being a bile acid TUDCA supports digestion and in particular the utilisation of fats and oils. The body only produces relatively small quantities of TUDCA, which can be negatively impacted by factors such as poor diet, microbiome dysbiosis (parasites, pathogens etc), gallbladder dysfunction, certain medications and impaired liver function. TUDCA is also readily available in supplemental form & has come a long way from the days of sourcing it from bear bile – thankfully these days TUDCA supplements are not derived from animal sources.

TUDCA has been extensively studied for its benefits on liver and digestive health. TUDCA is known to help protect liver cells from damage caused by toxins and help reduce inflammation in the liver. Additionally, it has shown promise in treating and preventing certain liver diseases, such as non-alcoholic fatty liver disease (NAFLD) and liver cirrhosis. Studies have shown TUDCA to significantly lower raised liver enzymes (such as Serum ALT, AST and ALP) in patients with liver cirrhosis. Another study looking at TUDCA’s effects on liver function in patients with primary biliary cirrhosis found similar positive results.

TUDCA has also been shown to have protective effects on other organs, such as the brain (thanks to it’s ability to cross the blood brain barrier) in which case some interesting research has shown it’s potential role in treatment approaches with neurodegenerative disorders such as Alzheimer’s, Parkinson’s, Huntington’s and Motor Neuron Disease.

For an in-depth article on TUDCA I recommend taking a look at the previous blog post “Unlocking the Health Benefits of Tauroursodeoxycholic Acid (TUDCA)”

When it comes to liver support, TUDCA supplementation is certainly no new kid on the block, and bodybuilders have been well aware of TUDCAs liver supporting properties for a long time. There are several brands of TUDCA supplements on the market, but not all are created equal. When choosing a TUDCA supplement, it’s important to look for one that is high-quality, pure, and free from unwanted additives. Seek out a supplement that has been third-party tested and has good reviews from other users. Our online store in Australia stocks two of the best TUDCA supplements, BodyBio & LVLUP Health, like with all our supplements we do a thorough review before we choose to add to our store.