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T3 and T4, Doses, Cycles for Cutting & Weight Loss

Peak Hulk
(@peakhulk)
New Member

T3 and T4 have been recognized for their ability to enhance fat loss during cutting or dieting phases. However, due to their critical role as thyroid hormones, it is imperative to have a thorough understanding before considering supplementation with T3/T4 for bodybuilding purposes. In this article, we will outline the optimal dosage of T3/T4 for bodybuilding, side effects, supplements, cutting process, and discuss their significance in achieving desired physique transformations.

The thyroid gland, positioned at the base of the neck, exerts influence over various physiological functions such as brain development, heart function, and digestion. It produces biologically active hormones, T3 and T4, which are pivotal in regulating metabolism. T4, also known as thyroxine, is produced in higher quantities compared to T3, or triiodothyronine, and serves as a precursor to T3.

Approximately 40% of T4 in the body undergoes deiodination, a process that involves removal of an iodine group from its outer ring, to convert into T3. Once converted, T3 is utilized by cells in diverse tissues and glands of the body to facilitate oxygen delivery and energy generation. While the thyroid gland produces about 20% of the body’s total T3, the remaining 80% is synthesized outside the thyroid gland in other tissues. On average, individuals secrete approximately 10-22 mcg of T3 and 94-110 mcg of T4 daily.

Some bodybuilders have turned to Cytomel, a synthetic form of T3, for its more potent effects compared to Synthroid, in order to achieve rapid weight loss and enhance their performance, meet weight requirements, or reduce body fat to attain their desired physique.

Individuals who do not suffer from hypothyroidism may obtain synthetic T3 from unofficial sources like the black market or websites that sell research compounds such as peptides and SARMs. T3 may be available in various forms, including Cytomel, as well as generic liquids, capsules, or tablets. However, it’s crucial to note that the use of synthetic T3 for bodybuilding purposes should be approached with caution and under the guidance of a qualified healthcare professional, as it can carry potential risks and side effects.

Athletes typically follow a dosing regimen of 25-50 mcg of T3 on average for an 8-week period to augment fat loss. When using tablets or liquid forms, they often start with a dosage of 12.5 mcg and gradually increase by 12.5 mcg every 3 days until reaching 50 mcg.

During the contest period, athletes may continue to use 50 mcg of T3, although some coaches may gradually reduce the dosage a few weeks prior to the competition to minimize loss of lean mass or prevent muscle flattening on the day of the show. After the contest, most competitors follow a tapering-off protocol, decreasing their daily dosage by 12.5 mcg every 3 days and concluding the T3 cycle with a total of 12.5 mcg for the final 3 days. Those using capsule forms may choose to run 25 mcg throughout the duration or adopt a similar tapering method, depending on the concentration of each capsule.


Quote
Posted : 22/04/2025 5:46 pm
Cheryl Bullock
(@cheryl-bullock)
New Member

T3 and T4 have been recognized for their ability to enhance fat loss during cutting or dieting phases. However, due to their critical role as thyroid hormones, it is imperative to have a thorough understanding before considering supplementation with T3/T4 for bodybuilding purposes. In this article, we will outline the optimal dosage of T3/T4 for bodybuilding, side effects, supplements, cutting process, and discuss their significance in achieving desired physique transformations.

The thyroid gland, positioned at the base of the neck, exerts influence over various physiological functions such as brain development, heart function, and digestion. It produces biologically active hormones, T3 and T4, which are pivotal in regulating metabolism. T4, also known as thyroxine, is produced in higher quantities compared to T3, or triiodothyronine, and serves as a precursor to T3.

Approximately 40% of T4 in the body undergoes deiodination, a process that involves removal of an iodine group from its outer ring, to convert into T3. Once converted, T3 is utilized by cells in diverse tissues and glands of the body to facilitate oxygen delivery and energy generation. While the thyroid gland produces about 20% of the body’s total T3, the remaining 80% is synthesized outside the thyroid gland in other tissues. On average, individuals secrete approximately 10-22 mcg of T3 and 94-110 mcg of T4 daily.

Some bodybuilders have turned to Cytomel, a synthetic form of T3, for its more potent effects compared to Synthroid, in order to achieve rapid weight loss and enhance their performance, meet weight requirements, or reduce body fat to attain their desired physique.

Individuals who do not suffer from hypothyroidism may obtain synthetic T3 from unofficial sources like the black market or websites that sell research compounds such as peptides and SARMs. T3 may be available in various forms, including Cytomel, as well as generic liquids, capsules, or tablets. However, it’s crucial to note that the use of synthetic T3 for bodybuilding purposes should be approached with caution and under the guidance of a qualified healthcare professional, as it can carry potential risks and side effects.

Athletes typically follow a dosing regimen of 25-50 mcg of T3 on average for an 8-week period to augment fat loss. When using tablets or liquid forms, they often start with a dosage of 12.5 mcg and gradually increase by 12.5 mcg every 3 days until reaching 50 mcg.

During the contest period, athletes may continue to use 50 mcg of T3, although some coaches may gradually reduce the dosage a few weeks prior to the competition to minimize loss of lean mass or prevent muscle flattening on the day of the show. After the contest, most competitors follow a tapering-off protocol, decreasing their daily dosage by 12.5 mcg every 3 days and concluding the T3 cycle with a total of 12.5 mcg for the final 3 days. Those using capsule forms may choose to run 25 mcg throughout the duration or adopt a similar tapering method, depending on the concentration of each capsule.


Quote
Topic starter Posted : 28/03/2026 3:54 pm
Cheryl Bullock
(@cheryl-bullock)
New Member

T3 and T4 have been recognized for their ability to enhance fat loss during cutting or dieting phases. However, due to their critical role as thyroid hormones, it is imperative to have a thorough understanding before considering supplementation with T3/T4 for bodybuilding purposes. In this article, we will outline the optimal dosage of T3/T4 for bodybuilding, side effects, supplements, cutting process, and discuss their significance in achieving desired physique transformations.

The thyroid gland, positioned at the base of the neck, exerts influence over various physiological functions such as brain development, heart function, and digestion. It produces biologically active hormones, T3 and T4, which are pivotal in regulating metabolism. T4, also known as thyroxine, is produced in higher quantities compared to T3, or triiodothyronine, and serves as a precursor to T3.

Approximately 40% of T4 in the body undergoes deiodination, a process that involves removal of an iodine group from its outer ring, to convert into T3. Once converted, T3 is utilized by cells in diverse tissues and glands of the body to facilitate oxygen delivery and energy generation. While the thyroid gland produces about 20% of the body’s total T3, the remaining 80% is synthesized outside the thyroid gland in other tissues. On average, individuals secrete approximately 10-22 mcg of T3 and 94-110 mcg of T4 daily.

Some bodybuilders have turned to Cytomel, a synthetic form of T3, for its more potent effects compared to Synthroid, in order to achieve rapid weight loss and enhance their performance, meet weight requirements, or reduce body fat to attain their desired physique.

Individuals who do not suffer from hypothyroidism may obtain synthetic T3 from unofficial sources like the black market or websites that sell research compounds such as peptides and SARMs. T3 may be available in various forms, including Cytomel, as well as generic liquids, capsules, or tablets. However, it’s crucial to note that the use of synthetic T3 for bodybuilding purposes should be approached with caution and under the guidance of a qualified healthcare professional, as it can carry potential risks and side effects.

Athletes typically follow a dosing regimen of 25-50 mcg of T3 on average for an 8-week period to augment fat loss. When using tablets or liquid forms, they often start with a dosage of 12.5 mcg and gradually increase by 12.5 mcg every 3 days until reaching 50 mcg.

During the contest period, athletes may continue to use 50 mcg of T3, although some coaches may gradually reduce the dosage a few weeks prior to the competition to minimize loss of lean mass or prevent muscle flattening on the day of the show. After the contest, most competitors follow a tapering-off protocol, decreasing their daily dosage by 12.5 mcg every 3 days and concluding the T3 cycle with a total of 12.5 mcg for the final 3 days. Those using capsule forms may choose to run 25 mcg throughout the duration or adopt a similar tapering method, depending on the concentration of each capsule.


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Topic starter Posted : 28/03/2026 3:54 pm
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